Chan Ho Park

Fellow

Plant Biology
Carnegie Institution for Science

Profile

Text: 

Chan Ho, Park, Ph. D.

 

Contact Address   

920 Clark Way, Palo Alto, CA 94304

Tel: 1-650-438-0648 / Mobile phone: 1-650-438-0648

E-mail: chpark@carnegiescience.edu / chanhop32@gmail.com

 

RESEARCH INTEREST

 

  • Receptor-mediated signal transduction pathways
  • Plant defense and growth cross-talk mechanism
  • Alternative Open Reading Frame peptides
  • Transport of plant growth regulators

 

EDUCATION

 

 Chung-Ang University, Seoul, Korea

Doctor of Philosophy in Biology (Unified course) (Mar. 2005 - Feb. 2010)

Master of Science in Biology (Unified course) (Mar. 2005 - Feb. 2010)

Bachelor of Science in Life Science (Mar. 1998 - Feb. 2004)

 

DISSERTATION

 

Ph. D. Dissertation

“Characterization and regulation of target genes of plant steroidal hormones, brassinosteroids”

Supervising professor: Seong-Ki Kim, Ph. D

 

 

RESEARCH EXPERIENCE

 

The young investigator research program of Chung-Ang University, Seoul, Korea (Sept. 2010 – Sept. 2011 )

 

Postdoctoral Research Fellow in Chung-Ang University, Seoul, Korea

 (Mar. 2010 – Mar. 2011)

Postdoctoral Research Fellow in Carnegie Institution for Science, Stanford, USA

 (Mar. 2011 – present)

Oral presentation at the 3rd International Brassinosteroid Conference, San Diego, USA

 (Aug. 1st-4th, 2018)

 

AREAS OF EXPERTISE

 

  • Signal transduction
  • Plant immunity & growth
  • Protein kinase & phosphatase
  • Proteomics
  • Protein-protein interaction
  • Protein-DNA interaction
  • Group management
  • Mentoring
  • Event organization

 

TECHNICAL SKILLS

 

  • Analysis of gene expression

- Reverse Transcription-Polymerase Chain Reaction (RT-PCR)

- Real Time-PCR

- RNA-seq

- GUS reporter analysis (GUS staining and GUS quantification)

- Promoter-deletion assay

  • Analysis of protein, protein-protein interaction and Proteomics

- Protein purification

- Western blot

- Confocal Microscopy

- Two Dimensional-Difference Gel Electrophoresis (2D-DIGE)

- Immunoprecipitation (IP)

- co-IP

- Protein mass spectrometry (MS)

- Quantitative MS analysis

- in-vitro kinase assay

- Immunocomplex kinase assay

- in-gel kinase assay

- Phosphatase assay

  • Protein-DNA interaction

- Electrophoretic mobility shift assay (EMSA)

- Chromatin immunoprecipitation (ChIP)

  • Pathogen-plant interaction

- Bacteria growth assay

- Bacteria flood inoculation assay

- Elicitor-induced defense response assays (MAP kinase, ROS, ect)

  • Generation of transgenic plant

- Agrobacterium-mediated plant transformation

- Intercross

  • Purification and quantification of natural compounds

- Solvent partitioning

- TLC

- Column chromatography

- HPLC

  • Analysis of ROS

- ROS assay

- DAP staining

  • Analysis of long-distance signaling

- Micrografting

 

TEACHING EXPERIENCE

 

Lecturer (Mar. 2010 – Dec. 2010)

Department of Life Science, Chung-Ang University, Seoul, Korea

 “Life Science” (Sept. 2010 – Dec. 2010)

 “General Biology and Experiment” (Mar. 2010 – Dec. 2010)

 

Teaching Assistant (Mar. 2005 – Dec. 2009)

Department of Life Science, Chung-Ang University, Seoul, Korea

“General Biology”

“Biochemistry”

“Plant Physiology”

“Plant Structure & Function”

 

 

ADDITIONAL EXPERIENCE

 

Supervisor of Nicole Xu (University of California, Berkeley) for Carnegie summer internship program (Jun. 2017 – Aug. 2017)     

Co-coordinator of the 2016 Carnegie summer internship program with Veder Garcia (Department of Plant Biology, Carnegie Institution for Science, Stanford, USA) (Jun. 2016 – Aug. 2016)

Supervisor of Nicole Xu (San Mateo High School) for Carnegie summer internship program (Jun. 2016 – Aug. 2016)

President of Biosmash (A tennis club of Korean scientists in Stanford and bay area) (Apr. 2013 – Apr. 2014)

 

RESEARCH AWARD

                             ▪ Best poster presentation award (2018 ASPB Western conference, Fullerton, CA)

 

PUBLICATIONS

 

  1. Chan Ho Park, Jeehee Roh, Ji-Hyun Youn, Seung-Hyun Son, Ji Hye Park, Soon Young Kim, Tae-Wuk Kim and Seong-Ki Kim (2018) Arabidopsis ACC oxidase 1 coordinated by multiple signals mediates ethylene biosynthesis and is involved in root development. (Molecules Cells, Accepted)

 

  1. Tae-Woo Kim, Ji-Hyun Youn, Tae-Ki Park, Eun-Ji Kim, Chan-Ho Park, Zhiyong Wang, Seong-Ki Kim, Tae-Wuk Kim (2018) OST1 Activation by the Brassinosteroid-Regulated Kinase CDG1-Like 1 in Stomatal Closure. Plant Cell 30(8): 1848-1863.

 

  1. Eun-Ji Kim, Se-Hwa Lee, Chan-Ho Park and Tae-Wuk Kim (2018) Functional Role of BSL1 Subcellular Localization in Brassinosteroid Signaling. Journal of Plant Biology 61(1): 40–49.

 

  1. Eun-Ji Kim, Ji-Hyun Youn, Chan-Ho Park, Tae-Woo Kim, Shenheng Guan, Shouling Xu, Alma L. Burlingame, Young-Pil Kim, Seong-Ki Kim, Zhi-Yong Wang and Tae-Wuk Kim (2016) Oligomerization between BSU1 Family Members Potentiates Brassinosteroi Signaling in Arabidopsis. Molecular Plant 9: 178–181.

 

  1. Min Fan, Ming-Yi Bai, Jung-Gun Kim, Tina Wang, Eunkyoo Oh, Lawrence Chen, Chan Ho Park, Seung-Hyun Son, Seong-Ki Kim, Mary Beth Mudgett, and Zhi-Yong Wang (2014) The bHLH Transcription Factor HBI1 Mediates the Trade-Off between Growth and Pathogen-Associated Molecular Pattern–Triggered Immunity in Arabidopsis. Plant Cell 26(2): 828-841.

 

  1. Chan Ho Park*, Mun-Seok Jang*, Ji Hyun Yun, Ji Eun Lee, Min Kyun Kim, Soon-Cheol Park and Seong-Ki Kim (2014) Effects of Secondary Mutation in det2-1 on Root Growth and Development in Arabidopsis. Journal of Plant Biology 57: 255-263. *equal contribution

 

  1. Seung-Hyun Son, Soo Chul Chang, Chan Ho Park, Seong-Ki Kim (2012) Ethylene negatively regulates EXPA5 expression in Arabidopsis thaliana. Physiologia Plantarum 144: 254–262.

 

  1. So yoon Jeong, Chan Ho Park, Min-Kyun Kim, Sang jun Nam, Jiheun Hong, Seong-Ki Kim (2012) Effect of Lysophosphatidylethanolamine and Brassinosteroids on Development of Arabidopsis Roots. Journal of Plant Biology 55: 178–184.

 

  1. Yew Lee*, Chan Ho Park*, A. Ram Kim, Soo Chul Chang, Soo-Hwan Kim, Woo Sung Lee, Seong-Ki Kim (2011) The effect of ascorbic acid and dehydroascorbic acid on the root gravitropic response in Arabidopsis thaliana. Plant Physiology and Biochemistry 49: 909-916. *equal contribution

 

  1. Sang Cheul Lee, Se-Hwan Joo, Chan-Ho Park, Seung-Hyun Son, Ji-Hyun Youn, Min-Kyun Kim, So-Yoon Jeong, Seong-Ki Kim (2011) Biosynthesis of Brassinosteroids in a Yeast (Saccharomyces cerevisiae) Cell, WAT21: Conversion of Teasterone to Castasterone. Bull. Korean Chem. Soc. 32(1): 332-334.

 

  1. Sang Cheul Lee, Tae Wuk Kim, Jung Yun Hwang, Chan Ho Park, Seung Hyun Son, Ji Hyun Youn, Seong Ki Kim (2010) Identification and Biosynthesis of Cholest-4-en-3-one and 6-Oxocholetanol in Young Tomato Plants. Bull. Korean Chem. Soc. 31(6): 1782-1784.

 

  1. Tae Wuk Kim, Se Hwan Joo, Jung Yun Hwang, Chan Ho Park, Sang Cheul Lee, Seung Hyun Son, Seong Ki Kim (2010) Identification of Castasterone from a Yeast (Saccharomyces cerevisiae) Strain, WAT21. Bull. Korean Chem. Soc. 31(5): 1430-1432.

 

  1. Chan Ho Park, Tae-Wuk Kim, Seung-Hyun Son, Jung-Yun Hwang, Sang Cheul Lee, Soo Chul Chang, Soo-Hwan Kim, Si Wouk Kim, Seong-Ki Kim (2010) Brassinosteroids control AtEXPA5 gene expression in Arabidopsis thaliana. Phytochemistry 71: 380-387.

 

  1. Chan-Ho Park, Takao Yokota, and Seong-Ki Kim (2009) 2-Deoxy-25-methyl- dolichosterone and 3-epi-2-Deoxy-25-methyldolichosterone in Immature Seeds of Phaseolus vulgaris. Bull. Korean Chem. Soc. 30(10): 2422-2424.

 

  1. Chan-Ho Park, Takao Yokota, and Seong-Ki Kim (2009) Characterization of 2-Epicastasterone from Immature Seeds of Phaseolus vulgaris. Bull. Korean Chem. Soc. 30(10): 2193-2194.

 

  1. Hye Ree Yun, Se-Hwan Joo, Chan Ho Park, Seong-Ki Kim, Soo Chul Chang and Soon Young Kim (2009) Effects of Brassinolide and IAA on Ethylene Production and Elongation in Maize Primary Roots. Journal of Plant Biology 52: 268-274.

 

  1. Se-Hwan Joo, Jung-Yun Hwang, Chan Ho Park, Sang Cheul Lee,  Seong-Ki Kim (2009) Biosynthetic Connection of 24-Methylene- and 24-Methyl-brassinosteroids in Phaseolus vulgaris. Bull. Korean Chem. Soc. 30(2): 502-504.

 

  1. Jung-Yun Hwang, Se-Hwan Joo, Chan Ho Park, Sang Cheul Lee, Seong-Ki  Kim(2009) Substrate Specificity for Cytochrome P450 85A1 and 85A2 in Brassinosteroids Biosynthesis. Bull. Korean Chem. Soc. 30(2): 293-294.

 

  1. Jung-Yun Hwang, Chan Ho Park and Seong-Ki Kim (2007) C-3 Epimerization of 6-Deoxocastasterone in Phaseolus vulgaris. Bull. Korean Chem. Soc 28(2): 175-176.

 

  1. Young-Soo Kim, Se-Hwan Joo, Jung-Yun Hwang, Chan Ho Park, and Seong-Ki Kim (2006) Characterization of C29-Brassinosteroids and Thier Biosynthetic Precursor in Immature Seeds of Phaseolus vulagris. Bull. Korean Chem. Soc. 27(8): 1117-1118.

 

  1. Jung Yun Hwang, Chan Ho Park, Ho Jin Namgung, Seong Ki Kim (2006) Identification of a New Brassinosteroid, 23-dehydro-2-epicastasterone from immature Seeds of Phaseolus vulgaris. Journal of Plant Biology 49: 409-412.