Wang Lab Publications

Selected Publications 

(see full publication list at:

Major Reviews:

Chaiwanon J, Wang W, Zhu JY, Oh E, Wang ZY. (2016) Information Integration and Communication in Plant Growth Regulation. Cell 164(6):1257-68. 

Wang W, Bai MY, Wang ZY.(2014). The brassinosteroid signaling network – a paradigm of signal integration. Curr. Opin. Plant Biol21:147–153.

Zhu JY, Sae-Seaw J, Wang ZY (2013). Brassinosteroid signalling. Development 140, 1615-1620. 

Wang ZY, Bai MY, Oh E, Zhu JY (2012). Brassinosteroid signaling network and regulation of photomorphogenesis. Annu. Rev. Genet46:701-724.

Kim TW and Wang ZY. (2010) Brassinosteroid signal transduction from receptor kinases to transcription factors.  Annu. Rev. Plant Biol. 61, 681-704.

Research articles

Yang Bi, Zhiping Deng, Weimin Ni, Zhenzhen Zhang, Dasha Savage, Thomas Hartwig, Sunita Patil, Juan A. Oses-Prieto, Kathy H. Li, Peter H Quail, Alma L Burlingame, Shou-Ling Xu, and Zhi-Yong Wang (2021). Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions. Nature Communication.

Garcia VJ, Xu SL, Ravikumar R, Wang W, Elliott L, Fesenko M, Altmann M, Falter-Braun P, Moore I, Assaad F, Wang ZY. (2020) TRIPP Is a Plant-specific Component of the Arabidopsis TRAPPII Membrane Trafficking Complex with Important Roles in Plant Development. Plant Cell. May 5:tpc.00044.2020. doi: 10.1105/tpc.20.00044. PMID: 32371545

Park CH, Youn JH, Xu SL, Kim JG, Bi Y, Xu N, Mudgett MB, Kim SK, Kim TW, & Wang ZY. (2019) BSU1 family phosphatases mediate Flagellin-FLS2 signaling through a specific phosphocode. BioRxiv doi:

Kim TW, Park CH, Hsu CC, Zhu JY, Hsiao Y, Branon T, Xu SL, Ting AY, and Wang ZY. (2019) Application of TurboID-mediated proximity labeling for mapping a GSK3 kinase signaling network in Arabidopsis. BioRxiv, doi:

Sun L, Feraru E, Feraru MI, Waidmann S, Wang W, Passaia G, Wang ZY, Wabnik K, Kleine-Vehn J. (2020). PIN-LIKES Coordinate Brassinosteroid Signaling with Nuclear Auxin Input in Arabidopsis thaliana.  Curr Biol. 30(9):1579-1588.e6. PMID: 32169207

Guo Z, Zhang Z, Yang X, Yin K, Chen Y, Zhang Z, Shin K, Zhu Q, Wang ZY, Wang W. (2020). PSBR1, encoding a mitochondrial protein, is regulated by brassinosteroid in moso bamboo (Phyllostachys edulis). Plant Mol Biol. 103(1-2):63-74. PMID: 32040757

Zhang X, Wu J, Yu Q, Liu R, Wang ZY, Sun Y. (2020). AtOFPs Regulate Cell Elongation by Modulating Microtubule Orientation via Direct Interaction with TONNEAU2. Plant Sci. 292:110405. PMID: 32005401

Zhao JL, Zhang LQ, Liu N, Xu SL, Yue ZL, Zhang LL, Deng ZP, Burlingame AL, Sun DY, Wang ZY, Sun Y, Zhang SW (2019). Mutual Regulation of Receptor-Like Kinase SIT1 and B'κ-PP2A Shapes the Early Response of Rice to Salt Stress. Plant Cell. 31(9):2131-2151. doi: 10.1105/tpc.18.00706. PMID: 31221736

Kim EJ, Lee SH, Park CH, Kim SH, Hsu CC, Xu S, Wang ZY, Kim SK, Kim TW. (2019). Plant U-Box40 Mediates Degradation of the Brassinosteroid-Responsive Transcription Factor BZR1 in Arabidopsis Roots. Plant Cell 31(4):791-808. doi: 10.1105/tpc.18.00941

Song L, Chen W, Wang B, Yao QM, Valliyodan B, Bai MY, Zhao MZ, Ye H, Wang ZY, Nguyen HT. (2019) GmBZL3 acts as a major BR signaling regulator through crosstalk with multiple pathways in Glycine max. BMC Plant Biol 19:86. doi: 10.1186/s12870-019-1677-2.

Tian Y, Fan M, Qin Z, Lv H, Wang M, Zhang Z, Zhou W, Zhao N, Li X, Han C, Ding Z, Wang W, Wang ZY, Bai MY. (2018). Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor. Nat Communication14;9(1):1063. 

Zhu J-Y, Li Y, Cao D, Yang H, Oh E, Bi Y, Zhu S, Wang Z-Y (2017) The F-box protein KIB1 mediates brassinosteroid-induced inactivation and degradation of GSK3-like kinases in Arabidopsis. Mol Cell 66(5):648-657.

Ni W, Xu SL, González-Grandío E, Chalkley RJ, Huhmer AFR, Burlingame AL, Wang ZY, Quail PH. (2017) PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3. Nat Communication8:15236. 

Xu SL, Chalkley RJ, Maynard JC, Wang W, Ni W, Jiang X, Shin K, Cheng L, Savage D, Hühmer AFR, Burlingame AL, Wang Z-Y. (2017) Proteomic Analysis Reveals O-GlcNAc Modification on Proteins with Key Regulatory Functions in Arabidopsis. PNAS 114(8):E1536-E1543. 

Bu SL, Liu C, Liu N, Zhao JL, Ai LF, Chi H, Li KL, Chien CW, Burlingame AL, Zhang SW, Wang ZY (2017)Immunopurification and Mass Spectrometry Identifies Protein Phosphatase 2A (PP2A) and BIN2/GSK3 as Regulators of AKS Transcription Factors in Arabidopsis. Mol Plant. 10(2):345-348. 

Zhu JY, Oh E, Wang T, Wang ZY. (2016) TOC1-PIF4 interaction mediates the circadian gating of thermoresponsive growth in Arabidopsis. Nat Communication 7:13692.

Zhang Z, Zhu JY, Roh J, Marchive C, Kim SK, Meyer C, Sun Y, Wang W, Wang ZY. (2016). TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis. Curr Biol. 26:1854-60.

Li C, Gu L, Gao L, Chen C, Wei CQ, Qiu Q, Chien CW, Wang S, Jiang L, Ai LF, Chen CY, Yang S, Nguyen V, Qi Y, Snyder MP, Burlingame AL, Kohalmi SE, Huang S, Cao X, Wang ZY, Wu K, Chen X, Cui Y. (2016) Concerted genomic targeting of H3K27 demethylase REF6 and chromatin-remodeling ATPase BRM in Arabidopsis. Nat Genet. 2016 Jun;48(6):687-93. 

Chaiwanon J and Wang ZY. (2015) Spatiotemporal brassinosteroid signaling and antagonism with auxin pattern stem cell dynamics in Arabidopsis roots. Current Biology 25(8):1031-42.

Ni WM, Xu SL, Tepperman JM, Stanley DJ, Maltby DA, Gross JD, Burlingame AL, Wang ZY and Quail PH(2014). A mutually assured destruction mechanism attenuates light signaling in ArabidopsisScience 344, 1160-1164.

Oh E, Zhu JY, Bai MY, and Wang ZY. (2014). A central transcription module regulates cell elongation and development by integrating major environmental and hormonal signals in Arabidopsis. eLife:e03031. 

Oh E, Zhu JY, Ryu H, Hwang I, Wang ZY. (2014). TOPLESS mediates brassinosteroid-induced transcriptional repression through interaction with BZR1. Nature Communications18;5:4140.

Fan M, Bai MY, Kim JG, Wang T, Oh E, Chen L, Park CH, Son SH, Kim SK, Mudgett MB, Wang ZY. (2014). The bHLH transcription factor HBI1 mediates the trade-off between growth and pathogen-associated molecular pattern-triggered immunity in Arabidopsis. Plant Cell 26, 828-841. 

Gendron JM, Liu JS, Fan M, Bai MY, Wenkel S, Springer PS, Barton MK, Wang ZY (2012). Brassinosteroids regulate organ boundary formation in the shoot apical meristem of Arabidopsis. Proc Natl Acad Sci USA 10921152-21157.

Bai MY, Fan M, Oh E, Wang ZY(2012) A triple-HLH/bHLH Cascade Controls Cell Elongation Downstream of Multiple Hormonal and Environmental Signaling Pathways in Arabidopsis. Plant Cell 24:4917-4929 

Oh E, Zhu JY, Wang ZY. (2012).  Interaction between BZR1 and PIF4 integrates brassinosteroid and environmental responses. Nature Cell Biol.14, 802-809. 

Bai MY, Shang JX, Oh E, Fan M, Bai Y, Zentella R, Sun TP, Wang ZY. (2012). Brassinosteroid, gibberellin, and phytochrome impinge on a common transcription module in Arabidopsis. Nature Cell Biol.14, 810-819. 

Kim TW, Michniewicz M, Bergmann DC, Wang ZY. (2012). Brassinosteroid regulates stomatal development by GSK3-mediated inhibition of a MAPK pathway. Nature 482, 419-422.

Hao Y, Oh E, Choi G, Liang Z, Wang ZY. (2012). Interactions between HLH and bHLH Factors Modulate Light-Regulated Plant Development. Mol. Plant 5, 688-697.

Kim TW, Guan S, Burlingame AL, Wang ZY. (2011). The CDG1 Kinase Mediates Brassinosteroid Signal Transduction from BRI1 Receptor Kinase to BSU1 Phosphatase and GSK3-like Kinase BIN2. Mol. Cell 43, 561-571.PMCID: PMC3206214

Tang W, Yuan M, Wang R, Yang Y, Wang C, Oses-Prieto JA, Kim TW, Zhou HW, Deng Z, Gampala SS, Gendron JM, Jonassen EM, Lillo C, DeLong A, Burlingame AL, Sun Y, Wang ZY. (2011). PP2A activates brassinosteroid-responsive gene expression and plant growth by dephosphorylating BZR1. Nature Cell Biol.13:124-131. PMCID: PMC3077550 

Sun Y, Fan XY, Cao DM, Tang W, He K, Zhu JY, He JX, Bai MY, Zhu S, Oh E, Patil S, Kim TW, Ji H, Wong WH, Rhee SY, Wang ZY. (2010). Integration of brassinosteroid signal transduction with the transcription network for plant growth regulation in Arabidopsis. Dev. Cell 19, 756-777. PMCID: PMC3018842.

Luo XM, Lin WH, Zhu S, Zhu JY, Sun Y, Fan XY, Cheng M, Hao Y, Oh E, Tian M, Liu L, Zhang M, Xie Q, Chong K, Wang ZY. (2010). Integration of light- and brassinosteroid-signaling pathways by a GATA transcription factor in Arabidopsis. Dev Cell 19: 872-883. 

Kim TW, Guan S, Sun Y, Deng Z, Tang W, Shang JX, Sun Y, Burlingame AL, Wang ZY. (2009) Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors. Nature Cell Biol11, 1254-1262. 

Tang W, Kim TW, Oses-PrietoJA,Sun Y, Deng Z, Zhu S, Wang R, Burlingame AL, Wang ZY (2008). BSKs mediate signal transduction from the receptor kinase BRI1 in Arabidopsis. Science 321, 557-560. 

Gampala SS, Kim TW, He JX, Tang W, Deng Z, Bai MY, Guan S, Lalonde S, Sun Y, Gendron JM, Chen H, Shibagaki N, Ferl RJ, Ehrhardt D, Chong K, Burlingame AL, Wang ZY. (2007). An essential role for 14-3-3 proteins in brassinosteroid signal transduction in Arabidopsis.Dev. Cell 13, 177-189. 

Bai MY, Zhang LY, Gampala SS, Zhu SW, Song WY, Chong K, Wang ZY. (2007). Functions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice. Proc.Natl. Acad. Sci. USA 104, 13939-13844.

He JX, Gendron JM, Sun Y, Gampala SS, Gendron N, Sun CQ, Wang ZY (2005). BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses. Science 307(5715): 1634-1638.

Wang ZY, Nakano T, Gendron J, He J, Chen M, Vafeados D, Yang Y, Fujioka S, Yoshida S, Asami T, Chory J(2002). Nuclear-localized BZR1 mediates brassinosteroid-induced growth and feedback suppression of brassinosteroid biosynthesis. Dev. Cell 2(4): 505-513.

Wang ZY, Seto H, Fujioka S, Yoshida S, Chory J. (2001) BRI1 is a critical component of a plasma membrane receptor for plant steroids. Nature 410(6826): 380-382.

He Z, Wang ZY, Li J, Zhu Q, Lamb C, Ronald P, Chory J. (2000) Perception of brassinosteroids by the extracellular domain of the receptor kinase BRI1. Science 288(5475): 2360-2363.

Weigel D, Ahn JH, Blázquez MA, Borevitz JO, Christensen SK, Fankhauser C, Ferrándiz C, Kardailsky I, Malancharuvil EJ, Neff MM, Nguyen JT, Sato S, Wang ZY, Xia Y, Dixon RA, Harrison MJ, Lamb CJ, Yanofsky MF, Chory J. (2000). Activation tagging in Arabidopsis. Plant Physiology 122(4): 1003-1013.

Wang ZY, Tobin EM (1998) Constitutive expression of the CIRCADIAN CLOCK ASSOCIATED 1(CCA1) gene disrupts circadian rhythms and suppresses its own expression. Cell 93(7): 1207-1217.